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Professor Ran Yuping’s team from the Department of Dermatology and Venereology reveals a newly discovered pathogenic Nocardia species


In August 2021 and April 2022, the team of Professor Ran Yuping from the Department of Dermatology and Venereal Diseases published papers successively in International Journal of systematic and evolutionary Microbiology, an authority on bacterial taxonomy, and British Journal of Dermatology, a journal in the field of dermatology, revealing a newly identified pathogenic Nocardia and its cutaneous infection case. The team named the newly discovered Nocardia strain "Nocardia huaxiensis sp. nov.". Dr. Zhuang Kaiwen from the Department is the first author, Professor Ran Yuping is the corresponding author, and West China Hospital of Sichuan University is the first author affiliation.


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Nocardiosis is a rare serious infectious disease caused by the invasion of the human body by the genus Nocardia, which can occur in immunosuppressed hosts as well as in immunocompetent individuals. The disease is mainly caused by inhalation of Nocardia spores through the respiratory tract, broken hyphal fragments or direct infection of the skin, involving multiple tissues and organs. In clinical practice, the diagnosis of Nocardia infection is extremely challenging, and it is easy to be misdiagnosed and missed.


link:

https://onlinelibrary.wiley.com/doi/10.1111/bjd.21599

https://www.microbiologyresearch.org/content/journal/ijsem/10.1099/ijsem.0.004970#tab2