The Gastric Cancer Center currently offers
the following subspecialties:
1. Gastric Cancer Surgery
This subspecialty is characterized by precision medicine and multidisciplinary
comprehensive treatment, focusing on standardized minimally invasive treatment
for gastric cancer, neoadjuvant therapy, precision diagnosis and treatment,
management of adenocarcinoma of the esophagogastric junction, and the
development of intelligent surgical platforms. It is committed to providing
scientifically standardized diagnostic and treatment plans for gastric cancer
patients to improve long-term outcomes. The team currently includes 18 senior
professional title holders, 9 doctoral supervisors, and 8 master's supervisors.
Among them are 1 principal investigator of a National 863 Program project, 1
Vice President of the Endoscopic Physicians Branch of the Chinese Medical
Doctor Association, 2 nationally recognized talents, 1 recipient of the
Ministry of Education's New Century Excellent Talents Support Program, 1 Chief
Expert of Health in Sichuan Province, and 8 Academic and Technical Leaders of
Sichuan Province. The team has achieved significant research outcomes in areas
such as capturing gastric cancer stem cells (Cell Res), uncovering
genetic characteristics and drug resistance mechanisms of gastric signet ring
cell carcinoma (Nat Commun), and CAR-T therapy for gastric cancer (Science
Advance). The team has led the development of three national consensus
statements on gastric cancer and established the Chinese Laparoscopic Surgical
Technique Assessment and Evaluation Standard System (CLSTA), leading the
advancement of the discipline.
2. Gastric Cancer Medical Oncology
As a specialized disease center, the Gastric Cancer Center manages one of the
highest volumes of gastric cancer cases in China. The Medical Oncology
subspecialty focuses on precise clinical staging of gastric cancer, stratified
perioperative treatment for locally advanced gastric cancer, and individualized
treatment strategies for advanced gastric cancer. The integration of surgical
and medical oncology within the center provides an excellent platform for
exploring precision perioperative treatment models. Currently, the center leads
nationally in laparoscopic exploration rates, neoadjuvant therapy rates, and
clinical research on neoadjuvant therapy for locally advanced gastric cancer.
For advanced gastric cancer, the center delivers precision individualized
treatment based on molecular biomarkers and sites of metastasis. Peritoneal
metastasis, one of the most common and prognostically unfavorable metastatic
sites in gastric cancer, has a low response rate to conventional chemotherapy
and immunotherapy. For advanced gastric cancer patients with peritoneal
metastasis, the center offers hyperthermic intraperitoneal chemotherapy
combined with systemic chemotherapy and immunotherapy, significantly improving
patient outcomes. In addition, the center conducts multiple clinical trials for
novel drugs and investigator-initiated trials for advanced gastric cancer. The
center provides "one-stop" multidisciplinary diagnosis, treatment,
and comprehensive management for every patient, achieving high overall patient
satisfaction.
3. Gastric Cancer Nutrition
As the chair unit of the Parenteral and Enteral Nutrition Branch of the Sichuan
Medical Association and its Youth Committee, this subspecialty focuses on
perioperative nutritional therapy for gastric cancer patients. It is nationally
renowned for clinical nutrition techniques including parenteral nutrition,
enteral nutrition, and oral nutritional supplements (ONS). The team provides
comprehensive nutritional support throughout the entire course of gastric
cancer treatment and standardized nutritional management during the neoadjuvant
period, achieving high patient satisfaction.
4. Gastrointestinal Stromal Tumors
(GIST)
Led by Professor Zhang Bo, the GIST subspecialty is dedicated to providing
individualized comprehensive diagnosis and treatment for patients with
gastrointestinal stromal tumors (GIST). It has established a multidisciplinary
team (MDT) and implements and promotes standardized, precise, and
individualized targeted therapy for GIST. The team possesses advanced treatment
concepts and extensive clinical experience in standardized surgical treatment,
adjuvant/neoadjuvant drug therapy, and comprehensive management of patients
with advanced GIST. The subspecialty provides patients with access to clinical
trials of novel anticancer drugs and has participated in multiple international
and domestic clinical studies on new GIST drugs. Core members of the
subspecialty hold key positions in major national academic organizations,
including Deputy Leader of the GIST Diagnosis and Treatment Expert Working
Group of the Surgeons Branch of the Chinese Medical Doctor Association, Vice
Chair of the GIST Expert Committee of the Chinese Society of Clinical Oncology
(CSCO), Standing Committee Member of the GIST Expert Committee of the Chinese
Anti-Cancer Association, Chair-Elect of the GIST Expert Committee of the
Sichuan Anti-Cancer Association, and Leader of the GIST Study Group of the
Surgeons Branch of the Sichuan Medical Doctor Association, among others. Core
members have also served as principal writers in the development of multiple
Asian and Chinese guidelines and consensus statements on GIST diagnosis and
treatment, with their research findings cited by international guidelines such
as the NCCN guidelines.
The subspecialty has received support from
multiple research funding sources, including three projects from the National
Natural Science Foundation of China, six projects from the Sichuan Provincial
Science and Technology Department, projects from the China Postdoctoral Science
Foundation, international and domestic multicenter clinical research projects,
and the hospital's 135 Project. It has published over 30 SCI-indexed papers.
In addition, our hospital manages
approximately 300–400 newly diagnosed GIST cases annually. Based on these
cases, the GIST subspecialty has established a comprehensive GIST database that
includes clinical and pathological information, genetic testing data, imaging
data, laboratory test indicators, and follow-up information. Currently, the
database contains over 3,000 GIST cases. The subspecialty conducts multiple
clinical studies, providing patients with access to clinical trials of novel
anticancer drugs. Regular patient education sessions are held to explore topics
such as disease etiology, pathology, and treatment advances, promoting disease
awareness and standardized treatment pathways. These efforts help patients and
their families develop a more systematic, in-depth, and intuitive understanding
of GIST, laying a solid foundation for promoting standardized treatment,
improving long-term treatment adherence, and enhancing follow-up compliance.