Recently, “Hepatitis B Virus Infection: Molecular Virology to Antiviral Drugs”, the English monograph on HBV, with Prof. Tang Hong as Editor in Chief, was officially published online by the internationally known Springer Publishing Company. In recent years, Prof. Tang Hong’s team has made a series of significant progress in the field of HBV research, especially in the regulation of HBV transcription and replication, and the antiviral therapy of chronic hepatitis B. Her team’s latest research entitled “Exosomal IFITM2 transmitted to DCs inhibits IFNα pathway activation and blocks anti-HBV efficacy of exogenous IFNα”, was published on the international authoritative hepatology journal--Hepatology (IF:14.079), providing an explanation to the suboptimal response of chronic hepatitis B patients to interferon treatment.
To review and update the achieved advances in the field of HBV study, Prof. Tang Hong invited the world-leading experts in HBV study including Prof. Alan McLachlan fromUniversity of Illinois, Prof. Su Lishan and Prof. Li Feng from University of North Carolina atChapel Hill, Prof. Lu Fengmin from Peking University, and Prof. Yang Dongliang from Huazhong University of Science and Technology, to compile this book. Associate Professor Li Hong from the Center of Infectious Diseases, West China Hospital of Sichuan University, served as the academic secretary to the Editor in Chief of this book.
This book provides a state-of-the-art review of the current understanding of HBV genome and life cycle, the regulation of HBV transcription and replication, and the immunopathogenesis of HBV. It also provides an update of the cell and animal models employed in HBV basic and preclinical research, and discusses the present and future therapies for chronic hepatitis B. This book may serve as a textbook for international students, or as a reference book for clinicians and researchers working in the field of HBV study.